In this notebook, I aim to create the interactome network from the Harvard CCSB Human Binary Interactome dataset.
http://interactome.dfci.harvard.edu/H_sapiens/index.php?page=download
The dataset involves a list of proteins that are known to interact with one another, based on their high-throughput screening experiments. It is simply a binary yes/no list of interactions; direction, strength, and other important data are not available.
In [2]:
import pandas as pd
import networkx as nx
dataset = pd.read_csv('HI-II-14.tsv', delimiter = '\t')
dataset
Out[2]:
Entrez Gene IDA
Symbol A
Entrez Gene IDB
Symbol B
0
14
AAMP
6293
VPS52
1
14
AAMP
8553
BHLHE40
2
14
AAMP
64782
AEN
3
15
AANAT
4188
MDFI
4
15
AANAT
8553
BHLHE40
5
28
ABO
65983
GRAMD3
6
28
ABO
84283
TMEM79
7
39
ACAT2
39
ACAT2
8
39
ACAT2
84708
LNX1
9
60
ACTB
60
ACTB
10
60
ACTB
71
ACTG1
11
60
ACTB
1072
CFL1
12
60
ACTB
1073
CFL2
13
60
ACTB
1962
EHHADH
14
60
ACTB
10486
CAP2
15
60
ACTB
11034
DSTN
16
60
ACTB
55093
WDYHV1
17
71
ACTG1
71
ACTG1
18
71
ACTG1
1072
CFL1
19
71
ACTG1
1073
CFL2
20
71
ACTG1
1962
EHHADH
21
71
ACTG1
10486
CAP2
22
71
ACTG1
11034
DSTN
23
71
ACTG1
28952
CCDC22
24
71
ACTG1
55093
WDYHV1
25
81
ACTN4
89
ACTN3
26
81
ACTN4
655
BMP7
27
81
ACTN4
51778
MYOZ2
28
87
ACTN1
87
ACTN1
29
87
ACTN1
89
ACTN3
...
...
...
...
...
13914
386681
KRTAP10-8
494514
TYMSOS
13915
386681
KRTAP10-8
653240
KRTAP4-11
13916
386681
KRTAP10-8
100131997
FAM27E3
13917
386682
KRTAP10-3
386682
KRTAP10-3
13918
386682
KRTAP10-3
388677
NOTCH2NL
13919
386682
KRTAP10-3
388818
KRTAP26-1
13920
386682
KRTAP10-3
389741
GLIDR
13921
386682
KRTAP10-3
390535
GOLGA8EP
13922
386682
KRTAP10-3
399761
BMS1P5
13923
386682
KRTAP10-3
401508
FAM74A4
13924
386682
KRTAP10-3
414157
C10orf62
13925
386682
KRTAP10-3
440023
KRTAP5-6
13926
386682
KRTAP10-3
441208
ZNRF2P1
13927
386682
KRTAP10-3
494514
TYMSOS
13928
386682
KRTAP10-3
653240
KRTAP4-11
13929
386682
KRTAP10-3
100131997
FAM27E3
13930
386684
KRTAP12-4
388677
NOTCH2NL
13931
387032
ZKSCAN4
387032
ZKSCAN4
13932
388677
NOTCH2NL
388818
KRTAP26-1
13933
388677
NOTCH2NL
399947
C11orf87
13934
388677
NOTCH2NL
401508
FAM74A4
13935
388677
NOTCH2NL
440023
KRTAP5-6
13936
388677
NOTCH2NL
653240
KRTAP4-11
13937
388818
KRTAP26-1
388818
KRTAP26-1
13938
388818
KRTAP26-1
440023
KRTAP5-6
13939
391257
SUMO1P1
391257
SUMO1P1
13940
441212
RP9P
441212
RP9P
13941
652968
GATSL3
652968
GATSL3
13942
653121
ZBTB8A
653121
ZBTB8A
13943
653316
FAM153C
100288778
LOC100288778
13944 rows × 4 columns
In [4]:
# Construct the network.
G = nx.Graph()
for row, data in dataset.iterrows():
G.add_edge(data['Symbol A'], data['Symbol B'])
G.node[data['Symbol A']]['gene_id'] = data['Entrez Gene IDA']
G.node[data['Symbol B']]['gene_id'] = data['Entrez Gene IDB']
In [6]:
G.nodes(data=True)[0]
Out[6]:
('UBE2E2', {'gene_id': 7325})
In [25]:
[n for n, d in G.nodes(data=True) if 'NFKB' in n]
Out[25]:
['NFKBID', 'NFKBIB', 'NFKBIA']
In [26]:
G.neighbors('ACTB')
Out[26]:
['EHHADH', 'CAP2', 'WDYHV1', 'ACTG1', 'DSTN', 'CFL1', 'CFL2', 'ACTB']
In [23]:
sorted(nx.degree_centrality(G).items(), key=lambda x: x[1], reverse=True)
Out[23]:
[('KRT40', 0.07275685727568572),
('KRTAP10-3', 0.06741050674105067),
('GOLGA2', 0.05764760576476057),
('NOTCH2NL', 0.05439330543933054),
('KRTAP10-7', 0.0502092050209205),
('KRT31', 0.04184100418410042),
('TRIM27', 0.04114365411436541),
('MEOX2', 0.04091120409112041),
('KRTAP10-8', 0.03835425383542538),
('KRTAP10-9', 0.03835425383542538),
('REL', 0.03719200371920037),
('MTUS2', 0.036494653649465365),
('LZTS2', 0.03533240353324035),
('RBPMS', 0.03370525337052534),
('SDCBP', 0.03114830311483031),
('TCF4', 0.030683403068340307),
('MDFI', 0.0299860529986053),
('TRAF1', 0.027661552766155277),
('FAM9B', 0.02719665271966527),
('AES', 0.026731752673175267),
('KRTAP10-5', 0.025569502556950254),
('CEP70', 0.02487215248721525),
('KRTAP5-9', 0.02394235239423524),
('TRAF2', 0.023477452347745235),
('PNMA1', 0.023245002324500233),
('TRIM54', 0.023245002324500233),
('MID2', 0.023012552301255228),
('TRIM23', 0.022547652254765224),
('LNX1', 0.022547652254765224),
('UBQLN1', 0.022547652254765224),
('TFIP11', 0.021617852161785217),
('USHBP1', 0.021385402138540212),
('CALCOCO2', 0.020688052068805207),
('ADAMTSL4', 0.019758251975825196),
('KIFC3', 0.019525801952580194),
('KRT15', 0.01882845188284519),
('SSX2IP', 0.018363551836355182),
('SIAH1', 0.018363551836355182),
('PSMA3', 0.01789865178986518),
('KRTAP10-1', 0.017433751743375175),
('WDYHV1', 0.017201301720130173),
('BANP', 0.016736401673640166),
('KRTAP4-2', 0.016736401673640166),
('SGTA', 0.016503951650395164),
('CEP57L1', 0.01580660158066016),
('CCDC155', 0.01580660158066016),
('TRIP6', 0.015574151557415155),
('AGTRAP', 0.015574151557415155),
('CCDC33', 0.015341701534170154),
('LMO2', 0.015341701534170154),
('HAUS1', 0.01510925151092515),
('CCNDBP1', 0.014644351464435146),
('FAM161A', 0.014644351464435146),
('IKZF3', 0.014644351464435146),
('TRIM42', 0.014644351464435146),
('CARD9', 0.014411901441190143),
('FHL3', 0.014411901441190143),
('APPBP2', 0.014179451417945141),
('BYSL', 0.014179451417945141),
('ZNF417', 0.014179451417945141),
('GMCL1', 0.01394700139470014),
('SPERT', 0.013714551371455136),
('SPRY2', 0.013482101348210134),
('IKZF1', 0.013249651324965132),
('C1orf94', 0.01301720130172013),
('PSMA1', 0.01301720130172013),
('KRTAP9-2', 0.012784751278475127),
('PIN1', 0.012552301255230125),
('CCHCR1', 0.012319851231985124),
('CCDC102B', 0.012319851231985124),
('CCDC136', 0.012319851231985124),
('THAP1', 0.011854951185495118),
('GLRX3', 0.011390051139005113),
('HOXA1', 0.011157601115760111),
('HMBOX1', 0.011157601115760111),
('DAZAP2', 0.011157601115760111),
('PHC2', 0.011157601115760111),
('TXLNA', 0.01092515109251511),
('TFCP2', 0.01092515109251511),
('SYNE4', 0.01092515109251511),
('STX11', 0.01092515109251511),
('AMOTL2', 0.010692701069270106),
('PRKAB2', 0.010460251046025104),
('KRT38', 0.010460251046025104),
('DAB1', 0.010460251046025104),
('CMTM5', 0.010460251046025104),
('PRPF31', 0.010460251046025104),
('FATE1', 0.010460251046025104),
('GORASP2', 0.010460251046025104),
('ABI2', 0.010227801022780102),
('KRT13', 0.010227801022780102),
('CEP55', 0.009995350999535099),
('VPS52', 0.009995350999535099),
('C1orf109', 0.009995350999535099),
('NCK2', 0.009995350999535099),
('STK16', 0.009762900976290097),
('ZNF587', 0.009762900976290097),
('NUP62', 0.009762900976290097),
('CCDC57', 0.009762900976290097),
('TNIP1', 0.009762900976290097),
('KRTAP4-12', 0.009762900976290097),
('VAC14', 0.009762900976290097),
('FSD2', 0.009530450953045095),
('SH2D4A', 0.009530450953045095),
('CEP76', 0.009298000929800092),
('PLSCR1', 0.009298000929800092),
('SCNM1', 0.00906555090655509),
('NECAB2', 0.00906555090655509),
('ZBTB8A', 0.00906555090655509),
('TRIM41', 0.00906555090655509),
('TRIP13', 0.00906555090655509),
('CEP44', 0.008833100883310088),
('TSGA10', 0.008833100883310088),
('BLZF1', 0.008600650860065086),
('PDE4DIP', 0.008600650860065086),
('MAGEA11', 0.008600650860065086),
('OTX1', 0.008368200836820083),
('AQP1', 0.008368200836820083),
('MRFAP1L1', 0.008368200836820083),
('SMARCE1', 0.008135750813575081),
('LDOC1', 0.008135750813575081),
('ZBTB14', 0.008135750813575081),
('PPP1R18', 0.008135750813575081),
('FBF1', 0.008135750813575081),
('CREB5', 0.008135750813575081),
('CDC23', 0.008135750813575081),
('MFAP1', 0.008135750813575081),
('MAGEA6', 0.008135750813575081),
('ZNF581', 0.00790330079033008),
('PNMA5', 0.00790330079033008),
('TRIM39', 0.00790330079033008),
('EIF4E2', 0.00790330079033008),
('CDR2', 0.00790330079033008),
('FXR2', 0.00790330079033008),
('HNRNPK', 0.00790330079033008),
('MIPOL1', 0.00790330079033008),
('CCDC146', 0.00790330079033008),
('DTX2', 0.007670850767085077),
('RINT1', 0.007670850767085077),
('CDCA7L', 0.007670850767085077),
('ARL6IP1', 0.007670850767085077),
('GOPC', 0.007670850767085077),
('C19orf66', 0.007670850767085077),
('HGS', 0.007670850767085077),
('UBE2I', 0.007670850767085077),
('AEN', 0.007438400743840074),
('ZNF250', 0.007438400743840074),
('TRAF4', 0.007438400743840074),
('ALAS1', 0.007438400743840074),
('NAB2', 0.0072059507205950715),
('PRKAA1', 0.0072059507205950715),
('MORF4L1', 0.0072059507205950715),
('CCDC36', 0.0072059507205950715),
('TPM3', 0.0072059507205950715),
('TEX11', 0.0072059507205950715),
('FAM90A1', 0.0072059507205950715),
('SUMO1P1', 0.0072059507205950715),
('LENG1', 0.0072059507205950715),
('LMO1', 0.0072059507205950715),
('TXLNB', 0.0072059507205950715),
('KLC3', 0.00697350069735007),
('INCA1', 0.00697350069735007),
('LONRF1', 0.00697350069735007),
('ZBTB24', 0.00697350069735007),
('SDCBP2', 0.00697350069735007),
('BHLHE40', 0.00697350069735007),
('PRKAA2', 0.00697350069735007),
('SPG21', 0.00697350069735007),
('CATSPER1', 0.00697350069735007),
('CRX', 0.006741050674105067),
('TCF12', 0.006741050674105067),
('HOMEZ', 0.006741050674105067),
('ZGPAT', 0.006741050674105067),
('KRTAP9-4', 0.006741050674105067),
('KRTAP26-1', 0.006741050674105067),
('ZNF572', 0.006741050674105067),
('ZCCHC10', 0.006741050674105067),
('KAT5', 0.006741050674105067),
('GRB2', 0.006741050674105067),
('TP53BP2', 0.006741050674105067),
('SYCE1', 0.006508600650860065),
('KRTAP3-2', 0.006508600650860065),
('NDEL1', 0.006508600650860065),
('KCTD9', 0.006508600650860065),
('LMO4', 0.006508600650860065),
('SUMO1', 0.006508600650860065),
('CLK2', 0.006276150627615063),
('VPS37C', 0.006276150627615063),
('KLHL12', 0.006276150627615063),
('SPAG5', 0.006276150627615063),
('PLEKHF2', 0.006276150627615063),
('RTP5', 0.006276150627615063),
('MAPKBP1', 0.006276150627615063),
('FAM74A4', 0.00604370060437006),
('KHDRBS2', 0.00604370060437006),
('MAGED1', 0.00604370060437006),
('TCEA2', 0.00604370060437006),
('KRTAP12-2', 0.00604370060437006),
('KRTAP5-6', 0.00604370060437006),
('EFHC2', 0.00604370060437006),
('DMRT3', 0.00604370060437006),
('NIF3L1', 0.00604370060437006),
('RBM39', 0.00604370060437006),
('NMI', 0.00604370060437006),
('FHL2', 0.005811250581125058),
('TXN2', 0.005811250581125058),
('MOS', 0.005811250581125058),
('CWF19L2', 0.005811250581125058),
('C6orf165', 0.005811250581125058),
('RCOR3', 0.005811250581125058),
('C1orf216', 0.005811250581125058),
('RGS20', 0.005811250581125058),
('NDC80', 0.005811250581125058),
('TMCC2', 0.005578800557880056),
('L3MBTL3', 0.005578800557880056),
('TAX1BP1', 0.005578800557880056),
('GEM', 0.005578800557880056),
('GOLGA8EP', 0.005578800557880056),
('FAM124B', 0.005578800557880056),
('CCDC67', 0.005578800557880056),
('BEND7', 0.005578800557880056),
('FAM124A', 0.005578800557880056),
('TCEANC', 0.005578800557880056),
('MKRN3', 0.005578800557880056),
('PRR20A', 0.005578800557880056),
('CBX8', 0.005346350534635053),
('STX4', 0.005346350534635053),
('BEX2', 0.005346350534635053),
('TADA2A', 0.005346350534635053),
('LCE4A', 0.005346350534635053),
('FARS2', 0.005346350534635053),
('ABI3', 0.005346350534635053),
('MED4', 0.005346350534635053),
('CAMK2B', 0.005346350534635053),
('EHHADH', 0.005346350534635053),
('EXOC5', 0.005346350534635053),
('ZNF564', 0.005346350534635053),
('ZMAT2', 0.005346350534635053),
('MORF4L2', 0.005346350534635053),
('FAM168A', 0.005346350534635053),
('DTNB', 0.005113900511390051),
('KLHL38', 0.005113900511390051),
('MBIP', 0.005113900511390051),
('AP1M1', 0.005113900511390051),
('PRR13', 0.005113900511390051),
('NUTM1', 0.005113900511390051),
('KPNA2', 0.005113900511390051),
('DDX6', 0.005113900511390051),
('ROPN1', 0.005113900511390051),
('LCE1B', 0.005113900511390051),
('SORBS3', 0.005113900511390051),
('ZNF446', 0.0048814504881450485),
('CCNC', 0.0048814504881450485),
('ATPAF2', 0.0048814504881450485),
('POLR1C', 0.0048814504881450485),
('TRIM69', 0.0048814504881450485),
('PTGER3', 0.0048814504881450485),
('ENKD1', 0.0048814504881450485),
('GMCL1P1', 0.0048814504881450485),
('CEP63', 0.0048814504881450485),
('DOCK8', 0.0048814504881450485),
('KANK2', 0.004649000464900046),
('MGAT5B', 0.004649000464900046),
('RUNX1T1', 0.004649000464900046),
('CTBP2', 0.004649000464900046),
('ZC2HC1C', 0.004649000464900046),
('ZNF124', 0.004649000464900046),
('TSC22D4', 0.004649000464900046),
('GABARAPL2', 0.004649000464900046),
('GPATCH2L', 0.004649000464900046),
('PDE9A', 0.004649000464900046),
('ARMC7', 0.004649000464900046),
('RHOXF2', 0.004649000464900046),
('TXNDC5', 0.004649000464900046),
('MEOX1', 0.004649000464900046),
('RPGRIP1', 0.004649000464900046),
('KRT19', 0.004416550441655044),
('FBXL18', 0.004416550441655044),
('AIMP2', 0.004416550441655044),
('TBC1D22B', 0.004416550441655044),
('MAD1L1', 0.004416550441655044),
('USP2', 0.004416550441655044),
('KANSL1', 0.004416550441655044),
('NME7', 0.004416550441655044),
('LCE3E', 0.004416550441655044),
('SNRPA', 0.004416550441655044),
('SF3B4', 0.004416550441655044),
('CHCHD3', 0.004416550441655044),
('NUFIP2', 0.004416550441655044),
('SMCP', 0.004416550441655044),
('ZFYVE21', 0.004416550441655044),
('IFT20', 0.004416550441655044),
('GFAP', 0.004416550441655044),
('TTC23', 0.004416550441655044),
('KCTD6', 0.004416550441655044),
('EXOSC8', 0.004416550441655044),
('VPS28', 0.004416550441655044),
('TCL1A', 0.004416550441655044),
('THAP7', 0.004416550441655044),
('FAM208B', 0.004416550441655044),
('RNF5', 0.004416550441655044),
('PNMA2', 0.004416550441655044),
('PUF60', 0.0041841004184100415),
('RUNDC3A', 0.0041841004184100415),
('IQUB', 0.0041841004184100415),
('TRIM37', 0.0041841004184100415),
('BLOC1S6', 0.0041841004184100415),
('KEAP1', 0.0041841004184100415),
('PIAS2', 0.0041841004184100415),
('SAT1', 0.0041841004184100415),
('TFPT', 0.0041841004184100415),
('EMD', 0.0041841004184100415),
('RBMY1F', 0.0041841004184100415),
('CKS1B', 0.0041841004184100415),
('CTBP1', 0.0041841004184100415),
('DOCK2', 0.0041841004184100415),
('ZNF20', 0.0041841004184100415),
('SPRY1', 0.0041841004184100415),
('CCDC53', 0.0041841004184100415),
('GCC1', 0.0041841004184100415),
('ZFYVE26', 0.00395165039516504),
('RASSF5', 0.00395165039516504),
('NEK6', 0.00395165039516504),
('VCP', 0.00395165039516504),
('C20orf195', 0.00395165039516504),
('MID1', 0.00395165039516504),
('CLEC7A', 0.00395165039516504),
('DTNBP1', 0.00395165039516504),
('TFG', 0.00395165039516504),
('RPL9', 0.00395165039516504),
('EPM2AIP1', 0.003719200371920037),
('ANKRD36BP1', 0.003719200371920037),
('TENC1', 0.003719200371920037),
('CHRD', 0.003719200371920037),
('RBMY1A1', 0.003719200371920037),
('ZBTB9', 0.003719200371920037),
('LCE2D', 0.003719200371920037),
('SOX5', 0.003719200371920037),
('CIB3', 0.003719200371920037),
('FAM154A', 0.003719200371920037),
('RABAC1', 0.003719200371920037),
('CREB3L1', 0.003719200371920037),
('LCE3C', 0.003719200371920037),
('KRT20', 0.003719200371920037),
('HOMER3', 0.003719200371920037),
('CHIC2', 0.003719200371920037),
('PRDM14', 0.003719200371920037),
('C14orf105', 0.003719200371920037),
('LASP1', 0.003719200371920037),
('FLJ32679', 0.003719200371920037),
('MAPK9', 0.003719200371920037),
('RBMX', 0.003486750348675035),
('MAGEB4', 0.003486750348675035),
('MAPK1IP1L', 0.003486750348675035),
('KXD1', 0.003486750348675035),
('SNRPC', 0.003486750348675035),
('HSD17B14', 0.003486750348675035),
('ZMIZ2', 0.003486750348675035),
('ATRIP', 0.003486750348675035),
('KRTAP10-11', 0.003486750348675035),
('SPG7', 0.003486750348675035),
('MORN3', 0.003486750348675035),
('GNE', 0.003486750348675035),
('MORN4', 0.003486750348675035),
('EFEMP2', 0.003486750348675035),
('KRTAP4-11', 0.003486750348675035),
('RBM41', 0.003486750348675035),
('ING5', 0.003486750348675035),
('RIMBP3', 0.003486750348675035),
('LDLRAD1', 0.003486750348675035),
('LGALS14', 0.003486750348675035),
('MAGEA12', 0.003486750348675035),
('TSG101', 0.003486750348675035),
('MAGOHB', 0.003486750348675035),
('TMEM79', 0.003486750348675035),
('NAA10', 0.003486750348675035),
('MCM7', 0.003486750348675035),
('SNRPB', 0.003486750348675035),
('DIP2A', 0.003486750348675035),
('SP100', 0.003486750348675035),
('TSHZ3', 0.003486750348675035),
('QRICH1', 0.003486750348675035),
('KCTD1', 0.003486750348675035),
('AMOT', 0.003486750348675035),
('C19orf57', 0.0032543003254300326),
('STAC3', 0.0032543003254300326),
('CLK3', 0.0032543003254300326),
('BCL6B', 0.0032543003254300326),
('RGS17', 0.0032543003254300326),
('TEKT4', 0.0032543003254300326),
('RAB3IP', 0.0032543003254300326),
('TRIM32', 0.0032543003254300326),
('SPATA8', 0.0032543003254300326),
('HNRNPC', 0.0032543003254300326),
('SKP1', 0.0032543003254300326),
('ZNF439', 0.0032543003254300326),
('UBXN11', 0.0032543003254300326),
('LMO3', 0.0032543003254300326),
('PSTPIP1', 0.0032543003254300326),
('LCE2A', 0.0032543003254300326),
('FRMD6', 0.0032543003254300326),
('DVL3', 0.0032543003254300326),
('DDIT3', 0.0032543003254300326),
('VPS37B', 0.0032543003254300326),
('HMG20A', 0.0032543003254300326),
('OSGIN1', 0.0032543003254300326),
('SRPK2', 0.0032543003254300326),
('FOS', 0.0032543003254300326),
('COIL', 0.0032543003254300326),
('CEP170P1', 0.0032543003254300326),
('MRPL11', 0.0032543003254300326),
('ACTN3', 0.0032543003254300326),
('FAM110A', 0.0032543003254300326),
('PTPMT1', 0.0032543003254300326),
('KRTAP4-7', 0.0032543003254300326),
('REEP6', 0.0032543003254300326),
('TEAD4', 0.00302185030218503),
('TRAF6', 0.00302185030218503),
('FAM13C', 0.00302185030218503),
('FUNDC1', 0.00302185030218503),
('JAKMIP2', 0.00302185030218503),
('TNFAIP1', 0.00302185030218503),
('HEXIM2', 0.00302185030218503),
('KPNA3', 0.00302185030218503),
('APIP', 0.00302185030218503),
('DCX', 0.00302185030218503),
('TCEB3', 0.00302185030218503),
('CDK18', 0.00302185030218503),
('HDAC4', 0.00302185030218503),
('TRAF5', 0.00302185030218503),
('ZBTB43', 0.00302185030218503),
('PEX5', 0.00302185030218503),
('AKAP9', 0.00302185030218503),
('OTUB2', 0.00302185030218503),
('ZNF490', 0.00302185030218503),
('ATP5O', 0.00302185030218503),
('NEBL', 0.00302185030218503),
('PPIG', 0.00302185030218503),
('EMILIN1', 0.00302185030218503),
('ZSCAN26', 0.00302185030218503),
('RBFOX2', 0.00302185030218503),
('SYT17', 0.00302185030218503),
('TBC1D16', 0.00302185030218503),
('HNRNPUL1', 0.00302185030218503),
('KLC4', 0.00302185030218503),
('PSME3', 0.00302185030218503),
('GABARAPL1', 0.00302185030218503),
('KIF9', 0.00302185030218503),
('KIAA1958', 0.00302185030218503),
('EHMT2', 0.00302185030218503),
('PAK7', 0.002789400278940028),
('EDA', 0.002789400278940028),
('TSSK3', 0.002789400278940028),
('SETBP1', 0.002789400278940028),
('TRIM38', 0.002789400278940028),
('RALBP1', 0.002789400278940028),
('EXOSC5', 0.002789400278940028),
('AHCYL1', 0.002789400278940028),
('POGZ', 0.002789400278940028),
('RFX6', 0.002789400278940028),
('ZMYND19', 0.002789400278940028),
('EIF4ENIF1', 0.002789400278940028),
('BEND5', 0.002789400278940028),
('KRT6A', 0.002789400278940028),
('CDC20B', 0.002789400278940028),
('RCHY1', 0.002789400278940028),
('COL8A1', 0.002789400278940028),
('KLHL2', 0.002789400278940028),
('JOSD1', 0.002789400278940028),
('ATF4', 0.002789400278940028),
('GLYCTK', 0.002789400278940028),
('CCNH', 0.002789400278940028),
('PPP1R16B', 0.002789400278940028),
('PID1', 0.002789400278940028),
('LUZP4', 0.002789400278940028),
('ZSCAN32', 0.002789400278940028),
('ARID5A', 0.002789400278940028),
('CNNM3', 0.002789400278940028),
('DYDC1', 0.002789400278940028),
('KRTAP12-1', 0.002789400278940028),
('ISCU', 0.002789400278940028),
('ACY3', 0.002789400278940028),
('TDO2', 0.002789400278940028),
('ALS2CR11', 0.002789400278940028),
('TCHP', 0.002789400278940028),
('ZNF792', 0.002789400278940028),
('CDKL3', 0.002789400278940028),
('SLC23A1', 0.002789400278940028),
('ZBTB7B', 0.002789400278940028),
('UTP23', 0.002789400278940028),
('ARFIP2', 0.002789400278940028),
('CAMK2D', 0.002789400278940028),
('GATA2', 0.002789400278940028),
('CCDC120', 0.002789400278940028),
('ZSCAN12', 0.002789400278940028),
('FANCL', 0.002789400278940028),
('RABGEF1', 0.002789400278940028),
('ZBTB38', 0.002789400278940028),
('MAPRE1', 0.0025569502556950256),
('SYT6', 0.0025569502556950256),
('SP4', 0.0025569502556950256),
('RECK', 0.0025569502556950256),
('WAC', 0.0025569502556950256),
('NEFL', 0.0025569502556950256),
('HNRNPLL', 0.0025569502556950256),
('HSPD1', 0.0025569502556950256),
('RAD54B', 0.0025569502556950256),
('CRCT1', 0.0025569502556950256),
('RSPH14', 0.0025569502556950256),
('EIF1AD', 0.0025569502556950256),
('YES1', 0.0025569502556950256),
('TXNDC9', 0.0025569502556950256),
('EIF4A2', 0.0025569502556950256),
('UBE2D4', 0.0025569502556950256),
('EWSR1', 0.0025569502556950256),
('RHOJ', 0.0025569502556950256),
('DHPS', 0.0025569502556950256),
('STAMBPL1', 0.0025569502556950256),
('TNNT1', 0.0025569502556950256),
('ZBTB25', 0.0025569502556950256),
('OPTN', 0.0025569502556950256),
('HNRNPF', 0.0025569502556950256),
('MTA1', 0.0025569502556950256),
('POLL', 0.0025569502556950256),
('PIH1D2', 0.0025569502556950256),
('BAHD1', 0.0025569502556950256),
('MYOG', 0.0025569502556950256),
('MLLT6', 0.0025569502556950256),
('ZBED1', 0.0025569502556950256),
('MXI1', 0.0025569502556950256),
('UBE2D1', 0.0025569502556950256),
('ACTN2', 0.0025569502556950256),
('SNW1', 0.0025569502556950256),
('ZNF410', 0.0025569502556950256),
('NXT2', 0.0025569502556950256),
('BIRC2', 0.0025569502556950256),
('DNAJA3', 0.0025569502556950256),
('RNF41', 0.0025569502556950256),
('HPCAL1', 0.0025569502556950256),
('GRN', 0.0025569502556950256),
('FAM118A', 0.0025569502556950256),
('TMEM239', 0.0025569502556950256),
('MAGEA4', 0.0025569502556950256),
('STAM2', 0.0025569502556950256),
('CXCL16', 0.0025569502556950256),
('CATIP', 0.0025569502556950256),
('BCL6', 0.0025569502556950256),
('WWP2', 0.0025569502556950256),
('RAD51D', 0.0025569502556950256),
('HSBP1', 0.0025569502556950256),
('PCSK5', 0.0025569502556950256),
('EDARADD', 0.0025569502556950256),
('ZNF24', 0.0025569502556950256),
('OIP5', 0.0025569502556950256),
('WT1-AS', 0.0025569502556950256),
('TRAF3IP3', 0.0025569502556950256),
('PGLS', 0.0025569502556950256),
('CHCHD2', 0.0025569502556950256),
('MYO15B', 0.002324500232450023),
('SSX2', 0.002324500232450023),
('PPL', 0.002324500232450023),
('SLC25A6', 0.002324500232450023),
('NEDD9', 0.002324500232450023),
('DZIP3', 0.002324500232450023),
('ZNF473', 0.002324500232450023),
('RNF111', 0.002324500232450023),
('ZSCAN21', 0.002324500232450023),
('SPATC1L', 0.002324500232450023),
('MAGEA1', 0.002324500232450023),
('FRS3', 0.002324500232450023),
('TTLL10', 0.002324500232450023),
('SFI1', 0.002324500232450023),
('PLEKHN1', 0.002324500232450023),
('LATS1', 0.002324500232450023),
('KRTAP2-4', 0.002324500232450023),
('C11orf57', 0.002324500232450023),
('CDKN1A', 0.002324500232450023),
('HOOK1', 0.002324500232450023),
('DACH1', 0.002324500232450023),
('RAB3IL1', 0.002324500232450023),
('RPIA', 0.002324500232450023),
('BCL2L13', 0.002324500232450023),
('HSPB7', 0.002324500232450023),
('CEP19', 0.002324500232450023),
('AP2B1', 0.002324500232450023),
('KIAA1683', 0.002324500232450023),
('NINL', 0.002324500232450023),
('TRPV6', 0.002324500232450023),
('ZNF329', 0.002324500232450023),
('PHF1', 0.002324500232450023),
('DHX57', 0.002324500232450023),
('ACTG1', 0.002324500232450023),
('ZNF471', 0.002324500232450023),
('RAD23A', 0.002324500232450023),
('NAGK', 0.002324500232450023),
('GATAD2B', 0.002324500232450023),
('POM121L8P', 0.002324500232450023),
('FAM76B', 0.002324500232450023),
('UBASH3B', 0.002324500232450023),
('CCNG1', 0.002324500232450023),
('SMN2', 0.002324500232450023),
('POLR2L', 0.002324500232450023),
('XIAP', 0.002324500232450023),
('FOXP2', 0.002324500232450023),
('EPS8', 0.002324500232450023),
('METTL17', 0.002324500232450023),
('SEC22A', 0.002324500232450023),
('DYNLL2', 0.002324500232450023),
('TRIM9', 0.002324500232450023),
('SS18L1', 0.002324500232450023),
('CUL3', 0.002324500232450023),
('NPBWR2', 0.002324500232450023),
('GSE1', 0.002324500232450023),
('CEP57', 0.002324500232450023),
('NGFRAP1', 0.002324500232450023),
('LSM2', 0.002324500232450023),
('TMSB4X', 0.002324500232450023),
('SH3GL1', 0.002324500232450023),
('ZNF398', 0.002324500232450023),
('CCDC101', 0.002324500232450023),
('TNIP3', 0.002324500232450023),
('SFN', 0.002324500232450023),
('ZBTB44', 0.002324500232450023),
('ATXN1', 0.002324500232450023),
('USP20', 0.002324500232450023),
('LIMS2', 0.002324500232450023),
('LIN37', 0.002324500232450023),
('MAL2', 0.002324500232450023),
('CPSF7', 0.002324500232450023),
('GABPB1', 0.002324500232450023),
('KRTAP19-5', 0.002324500232450023),
('ZNF165', 0.0020920502092050207),
('BMP7', 0.0020920502092050207),
('MBD3', 0.0020920502092050207),
('HDDC3', 0.0020920502092050207),
('MTMR9', 0.0020920502092050207),
('RBM17', 0.0020920502092050207),
('PRKAG1', 0.0020920502092050207),
('PSMA6', 0.0020920502092050207),
('ZNF697', 0.0020920502092050207),
('SSNA1', 0.0020920502092050207),
('TIFA', 0.0020920502092050207),
('BARD1', 0.0020920502092050207),
('SEC23B', 0.0020920502092050207),
('SNRPB2', 0.0020920502092050207),
('SNX1', 0.0020920502092050207),
('CENPP', 0.0020920502092050207),
('ZFP64', 0.0020920502092050207),
('SORBS2', 0.0020920502092050207),
('TYRO3', 0.0020920502092050207),
('CCDC172', 0.0020920502092050207),
('PKN1', 0.0020920502092050207),
('PRR3', 0.0020920502092050207),
('VENTX', 0.0020920502092050207),
('ZKSCAN4', 0.0020920502092050207),
('EAF1', 0.0020920502092050207),
('SNAPC5', 0.0020920502092050207),
('P4HA3', 0.0020920502092050207),
('TRIM21', 0.0020920502092050207),
('CRYAB', 0.0020920502092050207),
('MAPRE2', 0.0020920502092050207),
('DAAM2', 0.0020920502092050207),
('ZFC3H1', 0.0020920502092050207),
('ACTB', 0.0020920502092050207),
('SSX3', 0.0020920502092050207),
('SNAP47', 0.0020920502092050207),
('NPDC1', 0.0020920502092050207),
('AK8', 0.0020920502092050207),
('PGBD1', 0.0020920502092050207),
('FAM103A1', 0.0020920502092050207),
('ACTN1', 0.0020920502092050207),
('ARRDC3', 0.0020920502092050207),
('KRT6C', 0.0020920502092050207),
('KRTAP13-1', 0.0020920502092050207),
('ZNF488', 0.0020920502092050207),
('C8orf33', 0.0020920502092050207),
('UTP14C', 0.0020920502092050207),
('KHDRBS3', 0.0020920502092050207),
('DRAP1', 0.0020920502092050207),
('GATA1', 0.0020920502092050207),
('TSSC4', 0.0020920502092050207),
('ESRRG', 0.0020920502092050207),
('CDC73', 0.0020920502092050207),
('R3HDM2', 0.0020920502092050207),
('COX5B', 0.0020920502092050207),
('PBX3', 0.0020920502092050207),
('KATNAL1', 0.0020920502092050207),
('UBASH3A', 0.0020920502092050207),
('PIK3R2', 0.0020920502092050207),
('SSSCA1', 0.0020920502092050207),
('ROR2', 0.0020920502092050207),
('MRFAP1', 0.0020920502092050207),
('TRIP10', 0.0020920502092050207),
('TPM1', 0.0020920502092050207),
('MOB3C', 0.0020920502092050207),
('FAM107A', 0.0020920502092050207),
('SH3GLB1', 0.0020920502092050207),
('KRT6B', 0.0020920502092050207),
('TRIM36', 0.0020920502092050207),
('SEPT3', 0.0020920502092050207),
('CTAGE5', 0.0020920502092050207),
('FAM115A', 0.0020920502092050207),
('CARKD', 0.0020920502092050207),
('INO80E', 0.0020920502092050207),
('GFOD1', 0.0020920502092050207),
('ALDH3B1', 0.0020920502092050207),
('KRTAP12-4', 0.0020920502092050207),
('ZNF264', 0.0020920502092050207),
('MAPRE3', 0.0018596001859600185),
('SENP2', 0.0018596001859600185),
('QARS', 0.0018596001859600185),
('CDKN2D', 0.0018596001859600185),
('SMIM3', 0.0018596001859600185),
('DMC1', 0.0018596001859600185),
('UBE2K', 0.0018596001859600185),
('RSRC2', 0.0018596001859600185),
('BNIP3', 0.0018596001859600185),
('GRAMD3', 0.0018596001859600185),
('CADPS', 0.0018596001859600185),
('SPDL1', 0.0018596001859600185),
('CCDC114', 0.0018596001859600185),
('WIPF1', 0.0018596001859600185),
('EFS', 0.0018596001859600185),
('MAGEA2B', 0.0018596001859600185),
('SPATA3', 0.0018596001859600185),
('KLHL42', 0.0018596001859600185),
('MRPL28', 0.0018596001859600185),
('ZNF670', 0.0018596001859600185),
('CBS', 0.0018596001859600185),
('CCDC26', 0.0018596001859600185),
('ZNF148', 0.0018596001859600185),
('PIM1', 0.0018596001859600185),
('FOSL2', 0.0018596001859600185),
('CEP72', 0.0018596001859600185),
('MAB21L3', 0.0018596001859600185),
('GPKOW', 0.0018596001859600185),
('CCDC184', 0.0018596001859600185),
('PVRL2', 0.0018596001859600185),
('PPCDC', 0.0018596001859600185),
('FBXW5', 0.0018596001859600185),
('SRSF11', 0.0018596001859600185),
('SREK1IP1', 0.0018596001859600185),
('ZBTB26', 0.0018596001859600185),
('OAZ3', 0.0018596001859600185),
('TTC25', 0.0018596001859600185),
('CYTH4', 0.0018596001859600185),
('PEF1', 0.0018596001859600185),
('KIAA1217', 0.0018596001859600185),
('PHC1', 0.0018596001859600185),
('STK3', 0.0018596001859600185),
('GNAI2', 0.0018596001859600185),
('SH3KBP1', 0.0018596001859600185),
('BOLL', 0.0018596001859600185),
('NONO', 0.0018596001859600185),
('LHX4', 0.0018596001859600185),
('TNPO2', 0.0018596001859600185),
('SSC5D', 0.0018596001859600185),
('ALOX5', 0.0018596001859600185),
('HSD3B7', 0.0018596001859600185),
('SLC6A20', 0.0018596001859600185),
('NME1', 0.0018596001859600185),
('EIF4E', 0.0018596001859600185),
('PSMD9', 0.0018596001859600185),
('RNPS1', 0.0018596001859600185),
('NAV2', 0.0018596001859600185),
('TYMSOS', 0.0018596001859600185),
('EGLN3', 0.0018596001859600185),
('GLIDR', 0.0018596001859600185),
('NAPB', 0.0018596001859600185),
('FAM133A', 0.0018596001859600185),
('CFL2', 0.0018596001859600185),
('HBZ', 0.0018596001859600185),
('CBX2', 0.0018596001859600185),
('HOXB9', 0.0018596001859600185),
('KIAA1598', 0.0018596001859600185),
('CTNNBL1', 0.0018596001859600185),
('SNRNP25', 0.0018596001859600185),
('SFR1', 0.0018596001859600185),
('KDM1A', 0.0018596001859600185),
('HOOK2', 0.0018596001859600185),
('SMAD3', 0.0018596001859600185),
('BNIP3L', 0.0018596001859600185),
('NXF1', 0.0018596001859600185),
('APPL1', 0.0018596001859600185),
('SNAI1', 0.0018596001859600185),
('CALCOCO1', 0.0018596001859600185),
('RWDD2B', 0.0018596001859600185),
('MEMO1', 0.0018596001859600185),
('WASL', 0.0018596001859600185),
('GNMT', 0.0018596001859600185),
('SH3RF2', 0.0018596001859600185),
('TBC1D7', 0.0018596001859600185),
('ZNF655', 0.0018596001859600185),
('TEKT1', 0.0018596001859600185),
('TOLLIP', 0.0018596001859600185),
('RNF185', 0.0018596001859600185),
('CDA', 0.0018596001859600185),
('C11orf87', 0.0018596001859600185),
('CDKN2C', 0.0018596001859600185),
('UBXN1', 0.0018596001859600185),
('RNF8', 0.0018596001859600185),
('ATG9A', 0.0018596001859600185),
('SERTAD1', 0.0018596001859600185),
('FLNA', 0.0018596001859600185),
('TNK2', 0.0018596001859600185),
('LIN7A', 0.0018596001859600185),
('UBE2E2', 0.0016271501627150163),
('BAG3', 0.0016271501627150163),
('ZBTB16', 0.0016271501627150163),
('TNR', 0.0016271501627150163),
('PTK6', 0.0016271501627150163),
('TNFAIP3', 0.0016271501627150163),
('CCDC116', 0.0016271501627150163),
('UBE2D3', 0.0016271501627150163),
('KLHL32', 0.0016271501627150163),
('CA8', 0.0016271501627150163),
('NGLY1', 0.0016271501627150163),
('SSBP3', 0.0016271501627150163),
('ZNF440', 0.0016271501627150163),
('GNG5', 0.0016271501627150163),
('TNP2', 0.0016271501627150163),
('TRIM29', 0.0016271501627150163),
('UXT', 0.0016271501627150163),
('NR1D2', 0.0016271501627150163),
('INPP5D', 0.0016271501627150163),
('DCUN1D1', 0.0016271501627150163),
('FKBP1B', 0.0016271501627150163),
('ASPSCR1', 0.0016271501627150163),
('ZNF426', 0.0016271501627150163),
('TROAP', 0.0016271501627150163),
('SFTPC', 0.0016271501627150163),
('LDB1', 0.0016271501627150163),
('GPR25', 0.0016271501627150163),
('NEU4', 0.0016271501627150163),
('YIPF3', 0.0016271501627150163),
('FAM71C', 0.0016271501627150163),
('SULT2B1', 0.0016271501627150163),
('TULP3', 0.0016271501627150163),
('CRYAA', 0.0016271501627150163),
('YTHDC1', 0.0016271501627150163),
('RIBC1', 0.0016271501627150163),
('ARFGAP1', 0.0016271501627150163),
('SLC25A10', 0.0016271501627150163),
('AVPI1', 0.0016271501627150163),
('BIRC7', 0.0016271501627150163),
('TTC32', 0.0016271501627150163),
('DEF6', 0.0016271501627150163),
('ZNF138', 0.0016271501627150163),
('KRTAP10-4', 0.0016271501627150163),
('SEPT1', 0.0016271501627150163),
('KRT83', 0.0016271501627150163),
('MAGEA8', 0.0016271501627150163),
('CIRBP', 0.0016271501627150163),
('SLC15A3', 0.0016271501627150163),
('DUSP12', 0.0016271501627150163),
('ZNF266', 0.0016271501627150163),
('MAD2L2', 0.0016271501627150163),
('PBXIP1', 0.0016271501627150163),
('SEPT6', 0.0016271501627150163),
('RTN3', 0.0016271501627150163),
('CLNS1A', 0.0016271501627150163),
('RBCK1', 0.0016271501627150163),
('QKI', 0.0016271501627150163),
('FTL', 0.0016271501627150163),
('CALM3', 0.0016271501627150163),
('RNF213', 0.0016271501627150163),
('S100B', 0.0016271501627150163),
('PBLD', 0.0016271501627150163),
('LPXN', 0.0016271501627150163),
('DRG1', 0.0016271501627150163),
('MAL', 0.0016271501627150163),
('FAM189A2', 0.0016271501627150163),
('NLK', 0.0016271501627150163),
('EEF1G', 0.0016271501627150163),
('SPATA24', 0.0016271501627150163),
('PVRL3', 0.0016271501627150163),
('UBE3A', 0.0016271501627150163),
('DAXX', 0.0016271501627150163),
('NT5C2', 0.0016271501627150163),
('POM121', 0.0016271501627150163),
('TBC1D23', 0.0016271501627150163),
('LINC00526', 0.0016271501627150163),
('RALYL', 0.0016271501627150163),
('THAP10', 0.0016271501627150163),
('ZNF496', 0.0016271501627150163),
('FAM50B', 0.0016271501627150163),
('FAM64A', 0.0016271501627150163),
('LOC149950', 0.0016271501627150163),
('ZSCAN22', 0.0016271501627150163),
('RTN4', 0.0016271501627150163),
('NUDT14', 0.0016271501627150163),
('TRAPPC2L', 0.0016271501627150163),
('HSFY1', 0.0016271501627150163),
('PSMC6', 0.0016271501627150163),
('SRSF2', 0.0016271501627150163),
('RP9P', 0.0016271501627150163),
('CINP', 0.0016271501627150163),
('SNX20', 0.0016271501627150163),
('LURAP1', 0.0016271501627150163),
('PRTFDC1', 0.0016271501627150163),
('CARHSP1', 0.0016271501627150163),
('ABT1', 0.0016271501627150163),
('BAIAP2', 0.0016271501627150163),
('KLHL3', 0.0016271501627150163),
('GSTP1', 0.001394700139470014),
('TOX4', 0.001394700139470014),
('ZFP2', 0.001394700139470014),
('TRAF3IP2', 0.001394700139470014),
('PDCD6', 0.001394700139470014),
('FAM214B', 0.001394700139470014),
('QPRT', 0.001394700139470014),
('MED21', 0.001394700139470014),
('ANKRD40', 0.001394700139470014),
('RIPPLY1', 0.001394700139470014),
('ZNF32', 0.001394700139470014),
('PSMC3', 0.001394700139470014),
('MOB1A', 0.001394700139470014),
('BCAS2', 0.001394700139470014),
('PRPS2', 0.001394700139470014),
('LXN', 0.001394700139470014),
('NGB', 0.001394700139470014),
('ZNF483', 0.001394700139470014),
('CGGBP1', 0.001394700139470014),
('PSMB1', 0.001394700139470014),
('PLEKHB2', 0.001394700139470014),
('COL4A3BP', 0.001394700139470014),
('NDOR1', 0.001394700139470014),
('FAM127C', 0.001394700139470014),
('BMF', 0.001394700139470014),
('PARD6B', 0.001394700139470014),
('C5orf60', 0.001394700139470014),
('RNF31', 0.001394700139470014),
('KIAA0753', 0.001394700139470014),
('CSTF2', 0.001394700139470014),
('RBM3', 0.001394700139470014),
('CSRNP1', 0.001394700139470014),
('ZBTB48', 0.001394700139470014),
('EEF1D', 0.001394700139470014),
('TOP3B', 0.001394700139470014),
('LGALS3', 0.001394700139470014),
('IKBIP', 0.001394700139470014),
('FAM27E3', 0.001394700139470014),
('AGR2', 0.001394700139470014),
('U2AF2', 0.001394700139470014),
('PIN4', 0.001394700139470014),
('CAGE1', 0.001394700139470014),
('BAG5', 0.001394700139470014),
('CCDC153', 0.001394700139470014),
('ZNF101', 0.001394700139470014),
('EIF3D', 0.001394700139470014),
('RIC8A', 0.001394700139470014),
('KRT79', 0.001394700139470014),
('KRT8', 0.001394700139470014),
('FOXB1', 0.001394700139470014),
('U2AF1', 0.001394700139470014),
('ITGB5', 0.001394700139470014),
('POLR3C', 0.001394700139470014),
('RNF40', 0.001394700139470014),
('HMG20B', 0.001394700139470014),
('HPRT1', 0.001394700139470014),
('CTSZ', 0.001394700139470014),
('NCOA5', 0.001394700139470014),
('POP5', 0.001394700139470014),
('ZNF785', 0.001394700139470014),
('CCDC94', 0.001394700139470014),
('SIRPA', 0.001394700139470014),
('CDK6', 0.001394700139470014),
('NUP50', 0.001394700139470014),
('TTC19', 0.001394700139470014),
('ZC3H10', 0.001394700139470014),
('LSM3', 0.001394700139470014),
('SLC25A48', 0.001394700139470014),
('UBXN2B', 0.001394700139470014),
('L3MBTL2', 0.001394700139470014),
('PRAM1', 0.001394700139470014),
('TSNAX', 0.001394700139470014),
('ZNF26', 0.001394700139470014),
('SF1', 0.001394700139470014),
('RAB2B', 0.001394700139470014),
('TCF25', 0.001394700139470014),
('USO1', 0.001394700139470014),
('MARK4', 0.001394700139470014),
('BCL2L2', 0.001394700139470014),
('FGF12', 0.001394700139470014),
('CBX5', 0.001394700139470014),
('POLDIP3', 0.001394700139470014),
('C9orf9', 0.001394700139470014),
('FAM214A', 0.001394700139470014),
('CCNB1IP1', 0.001394700139470014),
('CAP2', 0.001394700139470014),
('GPSM3', 0.001394700139470014),
('MALL', 0.001394700139470014),
('SCAND1', 0.001394700139470014),
('VIM', 0.001394700139470014),
('CUTC', 0.001394700139470014),
('C1orf50', 0.001394700139470014),
('CHRNG', 0.001394700139470014),
('C10orf62', 0.001394700139470014),
('ZBTB22', 0.001394700139470014),
('PVR', 0.001394700139470014),
...]
In [ ]:
Content source: ericmjl/Flu-Interactome
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